About the Lab

Principal Investigator

Trevor Moraes

Dr. Moraes is a Professor in the Department of Biochemistry and a Tier II Canada Research Chair in the Structural Biology of Membrane Proteins.  He completed his undergraduate training in the  Department of Biochemistry at Queen’s University in 1997 and an MSc there with Dr. William Plaxton in 1999. He obtained his PhD in 2004 at the University of Alberta, supervised by Drs. Michael Ellison and J.N.Mark Glover, followed by post-doctoral studies with Dr. Natalie Strynadka at the University of British Columbia.

Lab Members

Christine Lai Christine Lai, lab manager
Christine Lai

I've been with the Moraes Lab since 2010 as a lab technician. My general interests are in understanding surface protein structure and function in pathogenic bacteria. Outside of the lab, I enjoy food, volleyball, and cats.

Chuxi Pan Chuxi Pan, technician
Chuxi Pan

Chuxi defended her Master's thesis in August 2019 and is currently working as a technician in the lab.

David Curran David Curran, Research associate
David Curran

Dave is a bioinformatician who completed his PhD from the University of Calgary on genomics and gene family evolution of nematodes. His main areas of expertise are software development and phylogenetics, and he works on many projects in collaboration with other members of the lab.

Epshita Islam Epshita Islam, Research associate
Epshita Islam

Epshita is developing vaccine products against several important human and veterinary bacterial pathogens by targeting essential nutrient acquisition systems.

Dixon Ng Dixon Ng, PDF
Dixon Ng

Dixon completed his PhD in Molecular Biology and Biochemistry at Simon Fraser University and a postdoctoral fellowship at the University of Calgary. He is currently working as a postdoctoral fellow, focusing on harnessing bacterial pathogenic mechanisms in vaccine antigen development and delivery.

Maciej Jagielnicki Maciej Jagielnicki, PDF
Maciej Jagielnicki

Maciej has completed his PhD studies in Biophysics at University of Virginia in 2018. He is currently working as a postdoctoral researcher specializing in membrane proteins and electron microscopy. Maciej's main project is structural investigation of SLAM proteins, which serve as outer membrane translocons for unfolded surface lipoproteins and lipoproteins in Gram-negative bacteria. On the road to structural insight into the transport mechanism of these proteins, a wide range of techniques is employed, such as membrane protein purification in nanodiscs, detergents and amphipols, fusion and mutant protein generation and testing, poly- and monoclonal antibody development and mammalian tissue culture. Structural work is performed on a 120kV screening electron microscope at MSB and 300kV Titan Krios data collection microscope at SickKids, both located within a 5 min walking distance from dr. Moraes' lab in MaRS West Tower.

Greg Cole Greg Cole, PDF
Greg Cole

Greg is a biochemist with a strong background in biophysics. He completed his PhD  in Biochemistry at the University of Toronto. He’s interested in structural characterization of challenging proteins, understanding the role of host-pathogen interactions in infection, and sampling local craft beer.

Esther Shin Esther Shin, PhD student
Esther Shin

Esther completed her undergraduate studies at Queen's University. Her PhD work focuses on the characterization of a novel surface protein in a Gram-negative bacterium and the identification of a small molecule inhibitor of a protein translocation pathway.

Tom Bateman Tom Bateman, PhD student
Tom Bateman

Tom completed his HBSc in Biochemistry at the University of Toronto. He is currently studying nutrient transport in the Gram-negative pathogen Acinetobacter baumannii.

Nick Ostan Nick Ostan, PhD student
Nick Ostan

Nick joined our lab after completing an MSc in the Schryvers Lab (University of Calgary) and undergrad at Queen's University.

Sang Minh Huynh Sang Minh Huynh, PhD student
Sang Minh Huynh

Sang completed his BSc in Biochemistry at the University of Toronto. He currently works on a novel class of bacterial membrane proteins called Slams, investigating their mechanism of function.

Natalie Au Natalie Au, PhD student
Natalie Au

Natalie completed her BScH at UofTSc and began her MSc in Sept 2019.

Huong Nguyen Huong Nguyen, PhD student
Huong Nguyen

Huong completed her BScH in Biochemistry at the University of Toronto and began her MSc. in Sept 2019.

Anastassia Pogoutse Anastassia Pogoutse, science writer
Anastassia Pogoutse

Ana defended her PhD in April 2019 and currently helps the lab with writing and editing manuscripts, theses, and other scientific documents.

Matthew Giles Matthew Giles, PhD student
Matthew Giles

Matt is a PhD candidate in the Joint Education Program between the University of Toronto and University of Melbourne (Chris McDevitt's Lab). 

Lab Alumni

Cathy Horvatin (Lab manager)

Postdoctoral Fellows
Charles Calmettes  (PDF 2009-16) - Assistant Professor at INRS-Institut Armand-Frappier
Xiaoyun Bai (PDF Co-supervised with Dr. R. Reithmeier 2013-15) - Visiting PDF at the National Cancer Institute (NCI), Bethesda, MD, USA
Volodymyr Shnitsar (PDF Co-supervised with Dr. R. Reithmeier 2010-13) - Research and Development Chemist, Airboss of America

PhD Students
Yogesh Hooda (PhD 2018) - PDF in the Hegde Lab at the MRC-LMB

Master's Students
Fan Xia (MSc 2016) - PhD student in the Kelley Lab at the University of Toronto
Andrew Judd (MSc 2013) - Research Scientist at Green Relief
Rediet Taddese (MSc 2013) - Lead Consultant at Q&C

Undergraduates and Project Students
Flora ZhiQi Wang
Benjamin Zheng
Ashutosh Gupta
Yancheng Li
Brandon Mitchell

Sarah Soyoung Kim
Royce Chun Lai
Parnian Dolati Ardejani
Robert Lu
Linda En Ze Zhong
Marim Barghash
Alexandra Zimmer
Weike Liang
Judy Truong
Adrienn Goczi
Donghe Yang
Michelle Quah
Brandon Sit
Anastasia Bosc
River Jiang
David Guo
Henry Chang
Amanda Miles
YeeSoo Kim
David Shen
Anselm Hui
Duncan Holbrook-Smith
Hao Li
Kang Wei David Lui
Calvin Tang
Olof Fahleson
Justine Berson

Lab Events